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The Ahmedabad Mercantile Co-operative Bank Ltd. (AMCO Bank) was established on April 7, 1966, under the guidance of Shri Mohanbhai C. Patel, with its inaugural branch located on Relief Road in Ahmedabad. The bank was originally founded with the mission of promoting and protecting the interests of the local merchant and business community. This founding focus has since broadened, and the institution has grown significantly over the following decades.

Today, the bank operates as a Multi-State Scheduled Co-operative Bank, indicating its dual regulation under cooperative laws and its inclusion in the Second Schedule of the Reserve Bank of India (RBI) Act, a status it attained in 1996. This "Scheduled" status underscores its significant role within the broader Indian financial system. The bank's operations have expanded beyond Gujarat into Maharashtra, with a network of over 32 branches. Its general significance lies in its support for diverse segments of the economy, including professionals, medium and small enterprises, large-scale industries, and the handloom sector, positioning it as an important catalyst for socio-economic development in its operating regions.